叶鼎

个人简介：

1983年生，博士、教授，鱼类生物技术与种质创新团队Co-PI，中国实验动物学会水生实验动物专业委员会秘书长。在Science China Life Sciences, Development，PLOS Genetics，Endocrinology，Frontiers in Endocrinology等学术刊物上发表论文40余篇, 多篇高引论文和亮点推荐论文，授权国家发明专利多项。

学术成果：

围绕鱼类生殖细胞发育和生物技术研究方向，阐明了斑马鱼性腺发育和配子发生进程；解析了雄激素在鱼类性腺发育、配子发生、生殖行为中的调控作用；揭示了控制生殖干细胞向卵母细胞分化的关键因子及其作用机制；实现多种鱼类生精细胞的精细分型和鉴定；建成了普适性高的鱼类借腹生殖技术体系；实现用小型实验鱼快速生产草鱼、团头鲂等大型经济鱼的成熟精子。

研究方向：

1. 海水经济鱼类基因编辑和借腹生殖前沿育种技术研究；

2. 海洋活性物质评价实验鱼模型的定制与规模化生产。

近五年代表性论文：

1. Zhiqin Ren, Ding Ye*, Naike Su, Chaofan Wang, Lijia He, Houpeng Wang, Mudan He, Yonghua Sun. 2024. foxl2l is a germ cell-intrinsic gatekeeper of oogenesis in zebrafish. Zoological Research. DOI: 10.24272/j.issn.2095-8137.2024.046.

2. Ding Ye†, Tao Liu†, Yongming Li, Yaqing Wang, Wei Hu, Zuoyan Zhu, Yonghua Sun. Identification of fish spermatogenic cells through high-throughput immunofluorescence against testis with an antibody set. Front Endocrinol (Lausanne). 2023 Apr 3;14:1044318. doi: 10.3389/fendo.2023.1044318.

3. Qifeng Zhang†, Ding Ye†, Houpeng Wang, Yaqing Wang, Wei Hu, Yonghua Sun*, Zebrafish cyp11c1 Knockout Reveals the Roles of 11-ketotestosterone and Cortisol in Sexual Development and Reproduction, Endocrinology, 2021, 161(6): bqaa048.(2019-2020年度及2020-2021年度Endocrinology杂志高被引论文)

4. Ding Ye†, Xiaosi Wang†, Changyong Wei†, Mudan He, Houpeng Wang, Yaqing Wang, Zuoyan Zhu, Yonghua Sun. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019, 15(9): e1008306.

5. Ding Ye†, Lin Zhu†, Qinfeng Zhang, Feng Xiong, Houpeng Wang, Xiaosi Wang, Mudan He, Zuoyan Zhu, Yonghua Sun*. Abundance of Early Embryonic Primordial Germ Cells Promotes Zebrafish Female Differentiation as Revealed by Lifetime Labeling of Germline. Mar Biotechnol (NY). 2019, 21(2): 217-228.(Springer Nature 2019年度亮点论文)

6. Ding Ye*, Yi-Xuan Tu, Houpeng Wang, Mudan He, Yaqing Wang, Zhengfang Chen, Zhen-Xia Chen, Yonghua Sun*, A landscape of differentiated biological processes involved in the initiation of sex differentiation in zebrafish, Water Biology and Security, 2022, 1(3): 100059.

联系方式：

邮箱：996996@hainanu.edu.cn